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  • Title: [Thyroid and C-cell system function during prolonged rotation (morphobiochemical research)].
    Author: Plakhuta-Plakutina GI, Savina EA, Afonin BV.
    Journal: Kosm Biol Aviakosm Med; 1985; 19(6):54-7. PubMed ID: 4087862.
    Abstract:
    The thyroid and parathyroid glands of 65 Wistar rats centrifuged for 30 days at 1.1 and 2.0 G were examined histologically and biochemically. The centrifugation led to a higher activity to C-cells, an increased rate of thyro-calcitonin (TCT) synthesis and excretion, i.e. C-cell degranulation, and a significant (two-fold) increase of TCT in plasma. The stimulation effect of the TCT-producing system persisted during 7-post-rotation days and was very distinct in the animals exposed to 2.0 G. There were no morphological changes in the parathyroid glands or in the PTH concentration in the plasma.
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