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  • Title: Synthesis of 2'-end-modified 2'-5'-oligoadenylates.
    Author: Hayakawa Y, Nobori T, Noyori R.
    Journal: Nucleic Acids Symp Ser; 1985; (16):129-32. PubMed ID: 4088856.
    Abstract:
    Analogs of 2'5'-oligiadenylates (2-5As) have been prepared on the basis of the recently developed internucleotide-linkage formation via selective hydroxyl activation of N-unprotected nucleosides. The analogs synthesized include the trimeric cores having 2'-deoxyadenosine, cordycepin (3'-deoxyadenosine), and 2',3'-bisdeoxyadenosine at the 2' termini, and the tetramer with 2'-end 2'-deoxyadenosine.
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