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  • Title: [A special flicker fusion frequency method for detection of the effects of gerontopharmaceuticals exemplified by the L-eburnamonine study].
    Author: Plörer S, Gerstenbrand F, Lehmann HE, Saltuari L, Stralkowski E.
    Journal: Psychiatr Neurol Med Psychol (Leipz); 1985 Nov; 37(11):635-42. PubMed ID: 4089045.
    Abstract:
    A clear difference between active drug and placebo is not always found when using the ascending and descending thresholds of the critical flicker fusion test (CFF). We selected a test requiring attention and concentration and performed again the CFF after this 6-minute concentration-test (reactive CFF). This reactive CFF was then used in a double-blind study in 30 ambulant patients with cerebro-vascular arteriosclerosis treated for 8 weeks with 80 mg/day cervoxan or placebo. After the treatment period the reaction of the CFF after the 6-minute concentration-test demonstrated a significantly more frequent improvement of the vigilance in the Cervoxan group compared to the placebo group.
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