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  • Title: Permeability of membrane to potassium in hypochromic red cells with different specific density.
    Author: Vettore L, De Matteis MC, Antonini L.
    Journal: Acta Haematol; 1977; 58(3):145-51. PubMed ID: 409029.
    Abstract:
    In hypochromic anaemias (heterozygous beta-thalassaemia and iron deficiency anaemia) ligher red cells lose more K+ than heavier ones, following incubation at 37 degrees C for 24 h. Both in the light and heavy fractions two subpopulations of cells with different permeability to K+ can be separated by a new centrifugation after incubation. On the basis of the results, a relationship between K+ permeability and probability of survival in hypochromic cells is suggested.
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