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  • Title: [Importance of the qualitative composition of dietary proteins in the dietotherapy of ischemic heart disease patients].
    Author: Meshcheriakova VA, Samsonov MA, Paramonova EG, Karabasova MA, Plotnikova OA.
    Journal: Vopr Pitan; 1985; (6):3-8. PubMed ID: 4090400.
    Abstract:
    The effects of two isocaloric antiatherosclerotic diets (containing 120 g protein) differing in the amino acid composition of protein sources introduced were studied and compared in patients with coronary heart disease. Conventional protein sources were used in the first diet, whereas in the second diet, 15% of protein (by weight) was replaced by soybean protein isolate. A study was also made of the effect of dietetic management on lipid metabolism in blood serum. Hemocoagulation, capillary permeability, the kallikrein-kinin system, and immune responsiveness. An increase in the hypolipidemic effect of the diet was noted together with a decrease in the activity of the kallikrein-kinin system, capillary permeability, and body autosensitization upon introduction into the diet of soybean protein isolate. The increase of the protein quota as well as that attained by means of introducing in the diet of soybean protein isolate reduces the therapeutic effect of the diet on hemostasis.
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