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  • Title: [Patient with familial Mediterranean fever and amyloidosis].
    Author: Atanasova P.
    Journal: Vutr Boles; 1985; 24(5):93-6. PubMed ID: 4090459.
    Abstract:
    A patient is described, with genetic form of amyloidosis with family Mediterranean fever. The secondary amyloidosis, that developed as a complication, has been preceded by attacks of acute articular and abdominal pains of several years. Elevated level of ethicholanolon in urine was established as well as extremely high values of serum fibrinogen, admitted to be pathognomonic signs of family Mediterranean fever. The eposition of amyloidosis is confirmed via rectal and renal punch biopsy. In spite of the diffuse character of the deposited amyloid in the renal tissue, there were still no signs of glomerular sclerosis and clinicalf--normal depuration renal function was observed, with normal creatinine clearance and normal nitrogenous bodies in serum. A favourable effect of colchicine therapy was observed in the patients both as regards the acute attacks of the disease and as regards the renal involvement.
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