These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Early events in the infection of permissive cells with simian virus 40: adsorption, penetration, and uncoating.
    Author: Barbanti-Brodano G, Swetly P, Koprowski H.
    Journal: J Virol; 1970 Jul; 6(1):78-86. PubMed ID: 4097232.
    Abstract:
    The early events in the interaction of simian virus 40 (SV40) with permissive cells were investigated. Evidence is presented that 30 min after infection intact virions penetrate the nuclei of infected cells. The uncoating of the virus is carried out in the nuclei with a complete dissociation of the viral genome from the protein coat. Opening of the circular parental deoxyribonucleic acid (DNA), i.e., conversion of component I to component II of SV40 DNA, takes place after uncoating, followed by the appearance of a new component sedimenting faster than component I at alkaline pH.
    [Abstract] [Full Text] [Related] [New Search]