These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of amphetamine and methylphenidate on fixed-interval responding in the squirrel monkey.
    Author: Goethe KE, Isaac W.
    Journal: Pharmacol Biochem Behav; 1977 Jul; 7(1):79-82. PubMed ID: 410037.
    Abstract:
    The effects of oral doses of d-amphetamine and methylphenidate on a fixed-interval operant response were studied in four young male squirrel monkeys. A fixed-interval of 80 sec with a limited hold of 20 sec was used. Methylphenidate produced no observable changes in behavior, while d-amphetamine produced dose related changes in both the rate of responding and the temporal patterning of responses. Since dose levels used included, and exceeded, human clinical dosages, the present findings may have implications for future research involving the clinical use of these drugs.
    [Abstract] [Full Text] [Related] [New Search]