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  • Title: [Effect of quinestrol-chlormadinone acetate on the endometrium, cervix uteri and vaginal epithelium].
    Author: Schrodt U, Göretzlehner G.
    Journal: Endokrinologie; 1971; 57(2):254-9. PubMed ID: 4100550.
    Abstract:
    The effects of a combination of 4 or 5 mg quinestrol and 10 mg chlormadinone acetate on the female genitalia were studied in 15 women on the 14th, 21st, and 28th days of the cycle. The cervicotropic effect of quinestrol was stronger (studied by cervical mucus, Fern test, and opening of the os uteri) than its endometrial effect. Hormone withdrawal bleeding occurred overwhelmingly from proliferated endometrium. The chlormadinone acetate dose of 10 mg was sufficient to provoke an endometrial secretion in only 4 cases. Cervical, vaginal, and endometrial findings were functionally consistent.
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