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  • Title: Successful treatment of pseudomonas aeruginosa--ventriculitis with intraventricular gentamicin in a child with hydrocephalus.
    Author: Olsen L, Grotte G, Nordbring F.
    Journal: Scand J Infect Dis; 1977; 9(3):243-5. PubMed ID: 410097.
    Abstract:
    A hydrocephalic child, who was operated with a ventriculo-peritoneal shunt at the age of 1 month, developed ventriculitis due to Pseudomonas aeruginosa at 8 months. After removal of the shunt and successively increasing intramuscular and intraventricular doses of gentamicin the patient was cured and a new shunt could be inserted. As high 24-hour gentamicin level in the cerebrospinal fluid as 76 microgram/ml was reached without any apparent toxic signs.
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