These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Detection of human IgE antibody by a modified rat mast cell degranulation technique.
    Author: Korotzer JL, Haddad ZH, Lopapa AF.
    Journal: Immunology; 1971 Apr; 20(4):545-8. PubMed ID: 4101707.
    Abstract:
    A rat mast cell degranulation (R.M.C.D.) technique is described in detail. This method is shown to detect specific antibodies to rye grass pollen and purified factors thereof (rye Group I antigen). The antibody detected belongs to the IgE immunoglobulin class as evidenced by specific degranulation when the rat mast cells are passively sensitized with the sensitive subject's serum and challenged with a monospecific rabbit antimyeloma IgE antiserum. No significant mast cell degranulation is observed with serum alone, antigen alone, or when anti-IgG, IgA or IgM are used in this system in an appropriate set of controlled experiments.
    [Abstract] [Full Text] [Related] [New Search]