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  • Title: Effect of bleeding on in vivo in vitro colony-forming hemopoietic cells.
    Author: Pannacciulli IM, Massa GG, Saviane AG, Ghio RL, Bianchi GL, Bogliolo GV.
    Journal: Acta Haematol; 1977; 58(1):27-33. PubMed ID: 410214.
    Abstract:
    The effect of bleeding on spleen colony-forming units (CFU-S) and on in vitro colony-forming cells with colony-stimulating factor (CFU-C) and erythropoietin (CFU-E) has been evaluated. The in vivo and in vitro colony-forming cells of the bone marrow show a decrease which for the CFU-E, CFU-C follows a short-lived increase. In the spleen, all progenitor cells assayed have shown a significant and sustained increase.
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