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  • Title: Intraleucocytic immunoglobulin in eosiniophilia in man.
    Author: MacSween JM, Langley GR.
    Journal: Immunology; 1971 Jul; 21(1):61-8. PubMed ID: 4104288.
    Abstract:
    The washed buffy coat smears of fifteen normal subjects and forty-three patients with eosinophilia were examined by the immunofluorescence technique for the presence of intracellular immunoglobulin. Immunofluorescence was not present in any of the normal buffy coat smears. Five of the patients with eosinophilia (including a patient with eosinophilic collagenosis) demonstrated intraleucocytic immunofluorescence which was blocked by specific unconjugated antisera. In four of these patients there was reactivity with anti-IgG but not with anti-IgA or anti-IgM, while in the one patient with eosinophilic collagenosis there was intraeosinophilic fluorescence with anti-IgA only.
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