These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Physico-chemical properties of deamidase AG from Pseudomonas fluorescens AG possessing antitumor activity].
    Author: Rakov SS, Prozorovskiĭ VN, Grebenshchikova OG, Kondrat'eva NA.
    Journal: Vopr Med Khim; 1977; 23(4):503-8. PubMed ID: 411253.
    Abstract:
    Homogenous deamidase AG from Pseudomonas fluorescens AG was found to be a glycoprotein with molecular weight of about 13,000 daltons. The molecule consists apparently of four similar or identic subunits with molecular weight of about 30,000 daltons. The amino acid composition, N-terminal amino acids, the amount of chymotryptic peptides, containing 14C-carboxymethyl cysteine were studied. The enzyme exhibited distinct antitumoral effect on cells of Burkitt's lymphoma, sensitive to asparaginase, but did not exhibit marked cytotoxic action on cells of human ovarium cancer CaOV line, resistant to asparaginases.
    [Abstract] [Full Text] [Related] [New Search]