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  • Title: Isolation and characterization of IgG globulins in subacute sclerosing panencephalitis.
    Author: Karcher D, Matthyssens G, Lowenthal A.
    Journal: Immunology; 1972 Jul; 23(1):93-9. PubMed ID: 4114651.
    Abstract:
    Patients affected with subacute sclerosing panencephalitis were found to show high measles antibody activity; γ-globulin M-components were detected in the serum, cerebrospinal fluid and brain tissue. The relative antibody activity was different in the different IgGs separated by gel filtration. The γ-globulins were separated into several components by isoelectric focussing on a sucrose gradient and each showed different degrees of measles antibody activity. Better separation was achieved by isoelectric focusing than by gel chromatography.
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