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  • Title: Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.
    Author: von Kleist S, Chavanel G, Burtin P.
    Journal: Proc Natl Acad Sci U S A; 1972 Sep; 69(9):2492-4. PubMed ID: 4115954.
    Abstract:
    A glycoprotein present in normal human tissue is characterized that is neither organ- nor tumor-specific (nonspecific crossreacting antigen) and that crossreacts (by the Ouchterlony double-diffusion technique) with the carcinoembryonic antigen. This immunological relationship indicates common determinants on the molecules of both antigens. We demonstrate that the nonspecific crossreacting antigen is not a fragment of the carcinoembryonic antigen molecule.
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