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  • Title: Proteolipid and bone matrix calcification in vitro.
    Author: Ennever J, Boyan-Salyers B, Riggan LJ.
    Journal: J Dent Res; 1977 Aug; 56(8):967-70. PubMed ID: 411812.
    Abstract:
    Proteolipid was demonstrated to contain the nucleator of bone matrix calcification, in vitro. Crude phospholipid extracted from bone matrix was fractionated by gel filtration. A single, protein-containing fraction induced apatite crystallization in a metastable calcium phosphate solution. The fraction was identified as proteolipid. The result supports the validity of a microbiologic analogue for vertebrate calcification.
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