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  • Title: [Spontaneous regression of pulmonary metastases from hypernephroma: report of a case and review of literature (author's transl)].
    Author: Ludwig G, Jentzsch R, Nuri M.
    Journal: Med Klin; 1977 Dec 09; 72(49):2118-21. PubMed ID: 412043.
    Abstract:
    Until now there are reported some 60 cases of spontaneous regression of pulmonary metastases from hypernephroma. An own case is shown up: There was taken nephrectomy and following local radiation of hypernephroma in a 59 years old male patient in spite of pulmonary metastases. 8 months after operation these metastases had disappeared. There was no indication for any metastases in radiologic and scintigrafic examination even 4 years following up neither in lungs nor in other organ. The causality of hormones and autoantibodies - perphaps additionally stimulated by wound infection-in the phenomenon of spontaneous regression of pulmonary hypernephroma-metastases is discussed. According to the literature and to experience in an own case nephrectomy and following local radiation - possibly additional progesterone-therapy for one year - is recommended in hypernephroma even in case of pulmonary metastases.
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