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  • Title: Effects of sputum from patients with cystic fibrosis on the activity in vitro of 5 antimicrobial drugs on Pseudomonas aeruginosa.
    Author: Davis SD, Bruns WT.
    Journal: Am Rev Respir Dis; 1978 Jan; 117(1):176-8. PubMed ID: 413461.
    Abstract:
    By in vitro tests on 12 strains of Pseudomonas aeruginosa, sputum from patients with cystic fibrosis sharply increased the minimal bactericidal concentrations of polymyxin B and neomycin. Sputum had a lesser effect on tests with gentamicin and tobramycin and essentially none on tests with carbenicillin.
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