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  • Title: [Case report on a retinal complication in long-term-therapy with oral hormonal contraceptives (author's transl)].
    Author: Huismans H.
    Journal: Klin Monbl Augenheilkd; 1977 Nov; 171(5):781-6. PubMed ID: 414003.
    Abstract:
    An exudative retinal process was noticed in a 38-year-old woman who had taken oral hormonal contraceptives for about 8 years. An incidental finding was a fundus albipunctatus in combination with an euryblepharon. There was further a strange shading in the colour of fundus, perhaps identical with the well known Mizuophenomenon. It seems that the macula is starting point of this phenomenon (Fig. 3). Possibly exudative processes in the plexus chorioidei of brain, also are due to complications in the ZNS from contraceptives. A 38 year old woman, IV-para, was examined due to visual disturbance in the left eye. Exudative processes of the retina were found, corresponding to localized damage of the corneal blood vessels. This patient had used various oral contraceptives over a period of 8 years, and it is assumed that this may be a factor in the ophthalmological damage. A unique combination of a fundus albipunctatus and a euryblepharon was also observed. The patient also exhibited a retinal phototropic effect. It is conjectured that analogous processes to those causing ophthalmological damage may also cause cerebral or cerebrospinal damage.
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