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  • Title: Gamma-glutamyl transpeptidase in brain capillaries: possible site of a blood-brain barrier for amino acids.
    Author: Orlowski M, Sessa G, Green JP.
    Journal: Science; 1974 Apr 05; 184(4132):66-8. PubMed ID: 4150025.
    Abstract:
    A fraction containing capillaries and rich in gamma-glutamyl transpeptidase was isolated from homogenates of bovine brain cortex by density gradient centrifugation. The enzyme was localized in the endothelial cells by a histochemical procedure. gamma-Glutantyl transpeptidase may function in the transfer of some amino acids across the blood-brain barrier.
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