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  • Title: Histamine H2-receptors in the sheep bronchus and cat trachea: the action of burimamide.
    Author: Eyre P.
    Journal: Br J Pharmacol; 1973 Jun; 48(2):321-3. PubMed ID: 4150268.
    Abstract:
    Histamine-induced relaxation of the sheep bronchus was antagonized by burimamide but not by mepyramine, indicating the presence of H(2)-receptors. Mepyramine or burimamide alone produced partial antagonism of histamine-induced relaxation of the cat trachea. Both inhibitors added simultaneously effectively abolished the histamine response, suggesting that both H(1)- and H(2)-receptors are active in relaxing the cat trachea.
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