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  • Title: Choreo-athetosis and encephalopathy induced by phenytoin.
    Author: McLellan DL, Swash M.
    Journal: Br Med J; 1974 Apr 27; 2(5912):204-5. PubMed ID: 4151655.
    Abstract:
    Two patients with intractable epilepsy who had been treated with various combinations of anticonvulsant drugs developed phenytoin encephalopathy. In both patients choreo-athetoid involuntary movements were prominent. Blood phenytoin concentrations were above 30 mug/ml. When phenytoin was given in smaller doses and its level in the blood fell the involuntary movements and other clinical manifestations disappeared.
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