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  • Title: Serum-gamma-glutamyltranspeptidase (gamma-GT) and aspartate-aminotransferase (AspAT) activities in adult cattle with chronic Fasciola hepatica infection.
    Author: Simesen MG, Nansen P.
    Journal: Acta Vet Scand; 1974; 15(2):239-43. PubMed ID: 4153057.
    Abstract:
    Sera from adult cattle with fluke-infected and normal livers were analyzed for γ-GT and AspAT activities. The analyses revealed no significant increases in either γ-GT or AspAT values of the animals with fascioliasis as compared with the non-infected animals. The advanced chronic stage of the infection characterized by hepatic fibrosis, limited injury of parenchyma and low fluke burdens may explain the lack of enzymatic increase. Serum γ-GT og AspAT er blevet undersøgt hos voksent kvæg med og uden ikteinfektion. Der kunne ikke påvises signifikant forøget enzymaktivitet hos de inficerede dyr sammenlignet med de iktefri dyr. Dette forhold må antagelig ses i lys af infektionens fremskredne stadium, der er præget af hepatisk fibrosering, begrænsede parenchymskader og lave parasitbyrder.
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