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  • Title: Gamma-aminobutyric acid effects on pituitary gonadotropin secretion.
    Author: Ondo JG.
    Journal: Science; 1974 Nov 22; 186(4165):738-9. PubMed ID: 4153578.
    Abstract:
    Gamma-aminobutyric acid (GABA) injected into the third ventricle of male rats promotes the release of pituitary luteinizing hormone (LH) but not follicle-stimulating hormone. When GABA was injected directly into the pituitary it was ineffective in promoting LH release. This evidence suggests that GABA may play a role in controlling the discharge of hypothalamic luteinizing hormone releasing factor.
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