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  • Title: [Limulus test in diagnosis of acute meningitis (author's transl)].
    Author: Arístegui J, Juan S, Saitúa G, Hernández M.
    Journal: An Esp Pediatr; 1977 Nov; 10(11):835-42. PubMed ID: 415650.
    Abstract:
    We tried to evaluate the utility of the Limulus Test in the diagnosis of acute meningitis. The study was made in 60 patients divided in three groups: Group A, formed by 37 children affected by purulent meningitis of known etiology; Group B, formed by 10 children affected by purulent meningitis of unknown etiology; Group C, formed by 13 children with viral meningitis. The results were compared with a control group (Group D), of 10 healthy children. The results correlated with the etiology, the cuantitative count of germs/ml. in C.S.F. and the clinical evolution. The results indicated that the Test is a rapid, simple and useful tool for the detection of endotoxin in the C.S.F. of purulent meningitis caused by Gram negative germs.
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