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  • Title: Trout hepatic enzyme activation of aflatoxin B1 in a mutagen assay system and the inhibitory effect of PCBs1.
    Author: Stott WT, Sinnhuber RO.
    Journal: Bull Environ Contam Toxicol; 1978 Jan; 19(1):35-41. PubMed ID: 415776.
    Abstract:
    In summary, it was demonstrated that the trout PMF may be successfully employed in the Ames mutagen assay method by utilization of proper salts solution and a metabolic preincubation period at 25 degrees C. It has also been observed that, unlike the rat, pretreatment of rainbow trout with various PCBs decrease the mutagen assay response to AFB.
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