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  • Title: The pedicle in neurofibromatosis.
    Author: Mandell GA.
    Journal: AJR Am J Roentgenol; 1978 Apr; 130(4):675-8. PubMed ID: 416677.
    Abstract:
    Three cases of von Recklinghausen's disease (neurofibromatosis) are described, one with agenesis of a pedicle, another with multiple hypoplastic pedicles, and a third with bilateral hypoplastic pedicles producing a spondylolistesis. These peidcle deficiencies are manifestations of mesodermal dysplasia. Agenesis of the pedicle most likely represents a defect in chondrification. Hypoplasia probably represents a partial lack of development of the pedicle and the ipsilateral arch. Hypoplasia or agenesis of a pedicle should suggest the possibility of underlying neurofibromatosis.
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