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  • Title: Changes in the red blood cell membrane in protein-calorie malnutrition.
    Author: Brown KH, Suskind RM, Lubin B, Kulapongs P, Leitzmann C, Olson RE.
    Journal: Am J Clin Nutr; 1978 Apr; 31(4):574-8. PubMed ID: 416706.
    Abstract:
    Ten children with protein-calorie malnutrition (five with kwashiorkor, three with marasmus, and two with marasmic-kwashiorkor) were studied at hospital admission and during recovery for evidence of changes in red blood cell lipids, osmotic fragility, and chromium survival. On admission, the children had significantly higher-than-normal red blood cell membrane cholesterol and phospholipid, and an elevated cholesterol:phospholipid ratio. Both red blood cell osmotic fragility and red cell survivals were depressed. These measurements returned to normal limits with recovery.
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