These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Mechanism of thermal adaptation of membrane lipids in Tetrahymena pyriformis NT-1. Possible evidence for temperature-mediated induction of palmitoyl-CoA desaturase.
    Author: Nozawa Y, Kasai R.
    Journal: Biochim Biophys Acta; 1978 Apr 28; 529(1):54-66. PubMed ID: 416850.
    Abstract:
    The regulatory mechanism of a key enzyme, palmitoyl-CoA desaturase, involved in the adaptation to temperature shift was investigated by labeling Tetrahymena pyriformis cells with [14C]palmitic acid. The rate of conversion of [14C]palmitate to [14C]palmitoleate was shown to be dependent on incubation temperature and also to be maximal at 2 h after the shift 39.5 to 15 degrees C. Addition of cycloheximide before the temperature shift produced no increase in desaturation of [14C]palmitate after the shift. These data would provide evidence for temperature-triggered increase of palmitoyl-CoA desaturase level and are also discussed in relation to membrane fluidity.
    [Abstract] [Full Text] [Related] [New Search]