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  • Title: Immunology of reaginic allergy: in vitro studies.
    Author: Osler AG.
    Journal: Clin Exp Immunol; 1970 Jan; 6(1):13-23. PubMed ID: 4190338.
    Abstract:
    The use of human leucocytes for in vitro studies of histamine release is reviewed. Several theoretical aspects and applications of the in vitro procedure are discussed. These include sensitivity of the cells to antigen as a reflection of disease severity, in vitro assays of reagin and the effect of parenteral immunization on the activity of human reaginic and blocking antibodies.
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