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  • Title: Immunoglobulin-containing cells in non-tropical sprue.
    Author: Soltoft J.
    Journal: Clin Exp Immunol; 1970 Mar; 6(3):413-20. PubMed ID: 4193742.
    Abstract:
    Immunofluorescent microscopy studies of jejunal biopsies from ten patients with gluten-induced enteropathy are reported. Eight biopsies were examined before and five after onset of gluten-free diet. Fluorescent antisera specifically reacting with IgA, IgG and IgM were applied, and accordingly the cells were differentiated and quantitated. The immunofluorescence microscopy revealed an increased amount of immunoglobulin-containing cells in both treated and untreated cases of sprue. The distribution of the immunoglobulin-containing cells within the three immunoglobulin classes was significantly altered as the proportion of IgM- and IgG-containing cells was elevated.
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