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  • Title: Rabies group-specific ribonucleoprotein antigen and a test system for grouping and typing of rhabdoviruses.
    Author: Schneider LG, Dietzschold B, Dierks RE, Matthaeus W, Enzmann PJ, Strohmaier K.
    Journal: J Virol; 1973 May; 11(5):748-55. PubMed ID: 4196634.
    Abstract:
    Cell-associated ribonucleoprotein (RNP) was isolated from BHK-21 cells infected with several strains of rabies and rabies-related viruses. The RNP-antigen from rabies and related viruses induced the formation of complement-fixing, precipitating, and immunofluorescent antibodies, and proved to be the group-specific antigen common to all rabies viruses. Antigens of the envelope which induce virus-neutralizing antibodies are apparently determinative for the serotype of a virus as evidenced by two-way neutralization tests. A combination of these methods seems to be a useful approach to the serological grouping and typing of rhabdoviruses.
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