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  • Title: Surgery in children with homozygous sickle cell anaemia.
    Author: Bentley PG, Howard ER.
    Journal: Ann R Coll Surg Engl; 1979 Jan; 61(1):55-8. PubMed ID: 420496.
    Abstract:
    During the 25 years 1952--77 31 surgical procedures were performed on children aged up to 16 years with sickle cell anaemia (SCA). Six emergency operations were carried out, all for complications of SCA indistinguishable from the acute surgical conditions they mimicked. Seventeen minor operations were well tolerated and major surgery was undertaken 8 times, including 5 splenectomies for hypersplenism and increased transfusion requirements. The preparation for surgery by planned multiple transfusions and the indications for splenectomy are discussed. Recommendations are made for the preparation of patients for acute and routine surgery.
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