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  • Title: Acrosomal proteinase inhibitors in rhesus monkey (Macaca mulatta) oviduct fluid.
    Author: Stambaugh R, Seitz HM, Mastroianni L.
    Journal: Fertil Steril; 1974 Apr; 25(4):352-7. PubMed ID: 4206576.
    Abstract:
    Acrosomal proteinase inhibitors were found in rhesus monkey fallopian tubes. Spermatozoa contain a proteolytic enzyme in their acrosomal heads and which would be adversely affected by the presence of acrosomal proteinase inhibitors. The inhibitor concentration was high before ovulation, decreased to low levels around the time of ovulation, and rose to high levels again within 1-3 days after ovulation. Alpha-1-antitrypsin, alpha-2-macroglobulin and alpha-1-antichymotrypsin all followed this high-low-high pattern. Alpha-1-antitrypsin in human cervical mucus is found to follow a similar waxing and waning according to progesterone secretion.
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