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  • Title: [A double blind cross-over study with mepindolol-sulfate in patients with coronary heart disease (author's transl)].
    Author: Bonelli J, Magometschnigg D, Schober H, Kleinberger G, Pichler H, Kaik G.
    Journal: Wien Med Wochenschr; 1979 Oct 20; 129(19):541-6. PubMed ID: 42224.
    Abstract:
    UNLABELLED: The effect of mepindolol-sulfate (2 x 2.5 mg) was tested in 20 patients with coronary heart disease in a controlled study against placebo resp. propranolol (3 x 40 mg). RESULTS: 1. The frequency and intensity of anginal attacks were reduced significantly under mepindolol-sulfate therapy.-- 2. There was a significant improvement of ergometric exercise tolerance under mepindolol-sulfate therapy.--3. Additionally a reduction of ST-depression in ECG was found under mepindolol-sulfate.--4. In patients with coronary heart disease the clinical effect of mepindolol-sulfate in a daily dose of 2 x 2.5 mg was equal to propranolol in a daily dose of 3 x 40 mg.
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