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Title: Bicyclic pyrazolines, potential central nervous system depressants and antiinflammatory agents. Author: Krapcho J, Turk CF. Journal: J Med Chem; 1979 Feb; 22(2):207-10. PubMed ID: 423202. Abstract: The synthesis and CNS activity of a series of 34 substituted bicyclic pyrazolines are described. Ten of these compounds were also screened for antiinflammatory activity. One of the compounds (15) exhibited significant antiinflammatory activity in the carrageenan-induced edema test.[Abstract] [Full Text] [Related] [New Search]