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  • Title: The "ring sign" of necrotic pheochromocytoma.
    Author: Velasquez G, Nath PH, Zollikofer C, Valdez-Davila O, Castaneda-Zuniga WR, Formanek A, Amplatz K.
    Journal: Radiology; 1979 Apr; 131(1):69-71. PubMed ID: 424608.
    Abstract:
    Pheochromocytomas are usually hypervascular tumors exhibiting dense stain during angiography. The cystic nature of the neoplasm or tumor necrosis can result in failure of opacification of the mass or a central lucent area. Four cases of pheochromocytoma are described where a central avascular zone was surrounded by a dense rim of contrast, giving a "ring sign." Since this appearance is best seen in the capillary and venous phases, delayed films are essential.
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