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  • Title: Malignant transformation of polyostotic fibrous dysplasia.
    Author: Johnson CB, Gilbert EF, Gottlieb LI.
    Journal: South Med J; 1979 Mar; 72(3):353-6. PubMed ID: 424832.
    Abstract:
    We have described an unusual case of polyostotic fibrous dysplasia in a 25-year-old white woman who had malignant transformation into a mesenchymal tumor with widespread metastases and features of rhabdomyosarcoma. Masculinization also occurred with high plasma testosterone levels. A mechanism for the development of masculinizing features is discussed.
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