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  • Title: A retrospective and prospective study of serial CEA determinations in the early detection of recurrent colon cancer.
    Author: Martin EW, Cooperman M, King G, Rinker L, Carey LC, Minton JP.
    Journal: Am J Surg; 1979 Feb; 137(2):167-9. PubMed ID: 426170.
    Abstract:
    The results of the present study emphasize the importance of minimizing the time delay between a significant elevation in CEA and a second-look operation. Equally important are the frequency of serial determinations, a thorough understanding of the limitations of the assay, and careful evaluation of the clinical condition of the patient.
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