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  • Title: Activation of lordotic responding in female rats by suppression of serotonergic activity.
    Author: Zemlan FP, Ward IL, Crowley WR, Margules DL.
    Journal: Science; 1973 Mar 09; 179(4077):1010-1. PubMed ID: 4265759.
    Abstract:
    After systemic administration of several serotonergic antagonists, female rats that had been ovariectomized, adrenalectomized, and estrogen-primed showed lordotic responding. Lordosis could also be elicited after direct placement of serotonergic receptor blockers into hypothalamic sites known to contain serotonergic terminals. None of the treatments activated the soliciting component of the estrous behavior pattern of the female rat. It is postulated that the hypothalamus contains serotonergic terminals which suppress lordotic responding.
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