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Title: Simian virus 40-induced T and tumor antigens. Author: Potter CW, McLaughlin BC, Oxford JS. Journal: J Virol; 1969 Nov; 4(5):574-9. PubMed ID: 4311792. Abstract: Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found.[Abstract] [Full Text] [Related] [New Search]