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  • Title: Prevention by pyrazole of the effects of chronic ethanol administration on the redox states of the hepatic nicotinamide--adenine dinucleotide (phosphate) couples and on liver and brain tryptophan metabolism in the rat.
    Author: Punjani NF, Badawy AA, Evans M.
    Journal: Biochem J; 1979 Oct 15; 184(1):165-8. PubMed ID: 43138.
    Abstract:
    Chronic administration of pyrazole in the diet of rats does not cause toxicity and prevents the chronic effects of ethanol on: (1) the redox states of the hepatic NAD(P) couples; (2) liver tryptophan pyrrolase activity; (3) brain tryptophan and 5-hydroxytryptamine metabolism.
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