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Title: Membrane structure: lipid-protein interactions in microsomal membranes. Author: Trump BF, Duttera SM, Byrne WL, Arstila AU. Journal: Proc Natl Acad Sci U S A; 1970 Jun; 66(2):433-40. PubMed ID: 4317915. Abstract: The relationships of phospholipid to membrane structure and function were examined in hepatic microsomes. Findings indicate that normal microsomal membrane structure is dependent on lipid-protein interactions and that it correlates closely with glucose-6-phosphatase activity. Modification of most phospholipid with phospholipase-C is associated with widening of the membrane which can be reversed following readdition of phospholipid.[Abstract] [Full Text] [Related] [New Search]