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  • Title: [The hyposmolar-hyponatremic syndrome in hepatic cirrhosis. Possible role of ADH].
    Author: Cavatorta F, Brignole M, Queirolo C.
    Journal: Minerva Med; 1979 Mar 10; 70(12):845-52. PubMed ID: 431839.
    Abstract:
    Following some remarks on the hyposomolar-hyponatraemic syndrome and on the formation of free water, the possible aetiopathogenetic mechanisms of hyponatraemia in ascitogenous cirrhosis of the liver and in particular the role of ADH are considered. 3 cases out of 18 suffering from ascitic phase cirrhosis in whom inability to produce free water was accompanied by conserved urinary excretion of sodium are reported. One explanation might be the intervention of ADH or of an antidiuretic substance.
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