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  • Title: [Functional activity of the lymphocytes of mouse lymph nodes in a system of viral carcinogenesis].
    Author: Umanskiĭ IuA, Evsev'eva AI, Semenova-Kobzar' RA, Kushko LIa.
    Journal: Tsitologiia; 1979 Feb; 21(2):191-5. PubMed ID: 432958.
    Abstract:
    A study was made of the PHA-induced lymphocyte blastransformation (BT), and lymphocyte antitumor activity, using a model of progressive and regressive neoplastic process induced by the Moloney virus in mice BALB/c. The antitumor acitvity of lymphocytes was estimated by their ability to inhibit spheroid production by tumor cells. A lymphocyte BT and their antitumor activity was registered during a progressive growth of the tumor and its restoration as the tumor is regressing.
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