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  • Title: Hepatitis-associated antigen in sporadic cases of acute viral hepatitis.
    Author: Kelen AE, Hathaway AE, McLeod DA, Nagler FP.
    Journal: Can Med Assoc J; 1972 Jan 08; 106(1):32-5. PubMed ID: 4333004.
    Abstract:
    Serum specimens collected during the period from September 1970 to April 1971 from hospitalized patients and apparently healthy staff members at risk were tested for the presence of hepatitis-associated antigen (HAA) by the parallel use of three techniques: the complement fixation test, crossover-electrophoresis and immuno-electronmicroscopy.Out of a total of 204 persons investigated 63 (30.9%) were found to harbour the antigen. The HAA-positive sera originated almost exclusively from sporadic cases of acute viral hepatitis (clinically diagnosed as "infectious hepatitis" or "serum hepatitis"). The great majority of the hepatitis cases studied had a history of drug addiction.
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