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  • Title: Endocrine abnormalities in thalassemia major.
    Author: Costin G, Kogut MD, Hyman CB, Ortega JA.
    Journal: Am J Dis Child; 1979 May; 133(5):497-502. PubMed ID: 433875.
    Abstract:
    Endocrine function evaluations in 16 patients with beta-thalassemia indicate that hypogonadotropic hypogonadism, hypoparathyroidism, and reduced adrenocorticotropic hormone reserve occur frequently, whereas reduced growth hormone and thyroid reserve are less common manifestations. Hemosiderosis-induced damage of the endocrine glands seems to be the main cause for endocrine dysfunction in the patients studied.
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