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  • Title: Mitochondrial polyriboadenylate polymerase: relative lack of activity in hepatomas.
    Author: Jacob ST, Schindler DG, Morris HP.
    Journal: Science; 1972 Nov 10; 178(4061):639-40. PubMed ID: 4343765.
    Abstract:
    An enzyme that polymerizes adenylate residues from adenosine triphosphate was prepared from rat liver mitochondria and compared to similar preparations from the mitochondria of three hepatomas. Enzyme activity in the hepatomas was only 1 to 2 percent of that in normal liver.
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