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Title: Isolation of an infectious ribonucleoprotein from vesicular stomatitis virus containing an active RNA transcriptase. Author: Szilágyi JF, Uryvayev L. Journal: J Virol; 1973 Feb; 11(2):279-86. PubMed ID: 4347429. Abstract: A ribonucleoprotein complex (TNP) containing an active RNA polymerase was isolated from purified vesicular stomatitis virus particles. The TNP sedimented through a sucrose gradient as a single band and appeared under the electron microscope as discrete long filaments in a spiral configuration. TNP contained one major and two minor polypeptides, but not the polypeptides associated with the outer coat of vesicular stomatitis virus. BHK-21 clone 13 cells could be infected with TNP, yielding infectious virus particles.[Abstract] [Full Text] [Related] [New Search]